Folate-PEG2-amine KRAS 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1

5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1

2 nM for PKD1

with an IC50 value of 18 nM

leading to derangement of the cell membrane

Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death

Folate-PEG2-amine KRAS 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1Folate PEG2 amine is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1099829 15 8 Molecular Weight: 571. 59 Formula: C25H33N9O7 Chemical Name: (2S) 2 [(4 {[(2 amino 4 oxo 3,4 dihydropteridin 6 yl)methyl]amino}phenyl)formamido] 4 ({2 [2 (2 aminoethoxy)ethoxy]ethyl}carbamoyl)butanoic acid Smiles: NC1NC(=O)C2=NC(CNC3C=CC(=CC=3)C(=O)N[C@@H](CCC(=O)NCCOCCOCCN)C(O)=O)=CN=C2N=1 InChiKey: LKVMQAYNKYJHGM